Penetrating Advancements
GCH Brain Tumor Program Advances Pediatric Care
The GCH Brain Tumor Program, a critical entity within the hospital's pediatric cancer division, is making significant strides in managing and treating slow-growing tumors in children. This renowned program, under the guidance of world-class experts like Louis Constine, MD, is pioneering cutting-edge treatments and participating in clinical trials to improve outcomes for pediatric patients.
Despite brain tumors having lower survival rates compared to other pediatric cancers, the GCH team is dedicated to providing long-term care, particularly for those tumors that cannot be physically removed without risking neurological damage. The program's approach is holistic, encompassing not only medical care but also support programs like Family Connection and advisory councils.
In the realm of treatment, the GCH Brain Tumor Program is pursuing innovative strategies such as precision medicine, immunotherapies, and drug combinations. These treatments often target specific genetic mutations in tumor cells, employ novel immunotherapies like CAR-T cells and immune checkpoint inhibitors, and test new drug combinations in clinical trials.
The program's involvement in clinical trials is registered on platforms like ClinicalTrials.gov, evaluating new chemotherapy regimens, targeted agents, and supportive therapies to improve outcomes and reduce side effects. The GCH team works closely with other medical centers to determine the most effective treatments and when to utilize new therapies.
The growth and expansion of the GCH pediatric Hematology/Oncology division have enabled faculty to focus exclusively on their specialties, leading to improved patient care. This division was ranked among the top 50 children's hospital programs for pediatric cancer by U.S. News & World Report in 2023.
Howard Silberstein, MD, a professor of Neurosurgery, has led surgical procedures for brain tumor patients for over two decades. The Brain Tumor Program also collaborates with the medical center's Genetics team to identify rare conditions.
The arrival of Jamie Flerlage, MD, from St. Jude Children's Research Hospital this fall will bring new leadership to the GCH pediatric Hematology/Oncology division. Despite the challenges and heightened risks associated with brain tumor treatments, many children treated at GCH are doing well, according to Thompson Stone.
For the most accurate and current information about the GCH Brain Tumor Program's innovative treatments and clinical trials, consulting GCH's official website, recent publications, or clinical trial registries specifying GCH involvement is recommended.
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